PROCHECK: A program to check the stereochemical quality of protein structures

Laskowski RA; MacArthur MW; Moss DS; Thornton JM

Department of Biochemistry and Molecular Biology, University College, London WC1E 6BT, England.
Crystallography Department, Birkbeck College, Malet Street, London WC1E 7HX, England.

J. Appl. Cryst. 26: 283-291 (1993)

The PROCHECK suite of programs provides a detailed check on the stereochemistry of a protein structure. Its outputs comprise a number of plots in PostScript format and a comprehensive residue-by-residue listing. These give an assessment of both the overall quality of the structure, as compared with well-refined structures of the same resolution, and also highlight regions that may need further investigation. The PROCHECK programs are useful for assessing the quality not only of protein structures in the process of being solved, but also of existing structures and those being modelled on known structures.